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The stage is set for a fascinating top-flight contest as table-toppers Arsenal host rock-bottom Wolves to the their home ground.

Confirmed Sides

Arsenal have opted for a trio of alterations following the XI that endured a narrow defeat at Villa Park last weekend. William Saliba, the Swedish striker and the Brazilian winger all start in the lineup. Martin Ødegaard and Mikel Merino are named on the bench, while the Italian defender is absent. The centre-back is back after sitting out five matches due to injury.

The visitors also make three adjustments to their starting XI following being soundly beaten 4-1 at Molineux by United on Monday evening. Matt Doherty, the Brazilian midfielder and the South Korean forward start. Hoever and Jhon Arias are on the bench, while Jean‐Ricner Bellegarde is omitted altogether.

Confirmed Lineups

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Subs: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Bench: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Match Official: Robert Jones
VAR Official: John Brooks

The Setup

Good evening! And I mean, look at this …

The table reveals a striking picture. The hosts sit comfortably at the top of the table, while Wolves prop up the league.

… however, even though this will be the 42nd time the top side have played the team propping up the division – with 30 out of 41, with seven draws – who are responsible for two of the four historical shocks? Why, Wolves, that’s who! Therefore, although Mikel Arteta will surely be anticipating another victory, Rob Edwards must know that long shots occasionally find the target, and you never know. The start is at 8 o'clock in the evening GMT. Let's go!

^{(The remaining last-over-first victories in the modern top-flight era are Oldham Athletic's 1-0 win over United in March 1993, and Spurs – yeah, this one sounds a bit weird - defeating Liverpool in November 2008.)}